Amevive Worked, but Rebounds Bad

Amevive Worked, but Rebounds Bad
from Monica

Hello Ed: Just wanted to send a mail to say thank you ... and to share my experience on my two Amevive treatments. I think it's important to share our information with each other. When someone is looking to start a new drug, like I was, the first place I went was your site hoping to find out what others had gone through.

For me, Amevive worked 100%. My derm said I was one of the lucky ones. He has found only 1 in 4 people respond. The first time I was only clear for 20 days. That was depressing. But I went for a second round and I was clear from October to February. For me, a life time sufferer of this disease, it was a miracle. However, I never expected the flare up that I got when the drug wore off. It's worse than any I have had in my life. Lesions are everywhere. Some days it's just downright debilitating. I'm going to go ahead and try Enbrel now that it's available in Canada. I hope for the best even though what I've read on the side effects are scaring me a little, but as we all know, or at least finally come to resolve ourselves to, it's worth the risk — at least for now.

Thank you for taking the time to keep up this site so that we can share, learn, and even laugh at ourselves while trying to live our lives without leaving too much of ourselves on the living room carpet.

Best Regards, -Monica

*****

Ed’s Response: And thank you, Monica, for following up with your Amevive experience. Your Doctor’s statement that only 1 in 4 flakers respond can’t be quarreled with here (see, for example, letter from Dina H.), one does have to wonder how the drug ever got approved for the treatment of P. Amevive is not nearly as popular as ANY of the other biologics approved for P treatment in the U.S. Of course, some of that has to do with the in-office intramuscular injection required to take the drug, which for many is far less convenient than do-it-yourself subcutaneous injections possible with most of the other biologics for psoriasis.

But in any case you can’t argue with success. Though I’m not sure why you decided to try Enbrel, rather than go ahead with more courses of Amevive, I hope you find Enbrel — which you do give yourself through subcutaneous injection — works as well. I don’t think Enbrel has a “course” per se. If the drug subdues the P, people continue taking it until they must stop for whatever reason. I’ll keep my fingers crossed for you and look forward to further reports. -Ed

This Month's Mail | Archives